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OCR: aemia can Acquired and genetic forms of hyperlipi ain sites inoccur as a result of disturbances at four n t of VLDL the endogenous pathway: increased inp removal and impaired LPL-mediated triglyceride d remnant can cause hypertriglyceridaemia; impaire of removal results in a combined elevation oximately cholesterol and triglyceride levels of app ue to equal extent; and accumulation of LDL d ce leads to impaired LDL receptor-mediated clearan hypercholesterolaemia.